Professor Joanna Bridger
Professor
Heinz Wolff 107
- Email: joanna.bridger@brunel.ac.uk
- Tel: +44 (0)1895 266272
- Biosciences
Summary
Our research concerns how the genome is spatially organised, influenced and manipulated within its environment, the cell nucleus. The group has had a number of major advances and is currently focused on aspects of genome behaviour in replicative senescence, the premature ageing disease Hutchinson-Gilford Progeria Syndrome, host:pathogen interactions and female cancers. We are wish to understand how structures such as the nuclear lamina, nucleoskeleton and nuclear motors influence the functionality of the genome in health and disease.
Our newest interest is in how the genome can be organised and regulated in low gravity situations and space.
Qualifications
HND BTEC Applied Biology 1985
BSc Microbiology and Genetics, UCL 1990
PhD in Zoology, Chromatin Organisation by the Nuclear Lamina. The University Dundee 1994
PGCert in L&T, ÃÛÌÒ´«Ã½ 2002
MA in Cult Film and TV, ÃÛÌÒ´«Ã½, 2010
Responsibility
Director of the Centre for Genome Engineering and Maintenance (cenGEM)
Co-head Brunel Space Travel and Applied Research (B-STAR) Network
Newest selected publications
Garimberti, E., Federico, C., Ragusa, D., Bruno, F., Saccone, S., Bridger, JM. and et al. (2024) ''. International Journal of Molecular Sciences, 25 (4). pp. 1 - 12. ISSN: 1661-6596
Schirmer, EC. and Bridger, JM. (2023) ''. Frontiers in Cell and Developmental Biology, 11. pp. 1 - 2. ISSN: 2296-634X
Silahtaroglu, A., Bridger, JM. and Lei, EP. (2022) ''. Scientific Reports, 12 (1). pp. 1 - 2. ISSN: 2045-2322
Bridger, JM., Torres Pereira, R., Pina, C., Tosi, S. and Lewis, A. (2022) 'Alterations to Genome Organisation in Stem Cells, their Differentiation and Associated Diseases', in Kloc, M. and Kubiak, JZ. (eds.) Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine. Cham, Switzerland : Springer. , 70. pp. 71 - 102. ISBN 10: 3-031-06573-5. ISBN 13: 978-3-031-06572-9.
Barravecchia, I., De Cesari, C., Forcato, M., Scebba, F., Pyankova, O., Bridger, J., et al. (2021) ''. Cellular and Molecular Life Sciences, 79 (1). pp. 1 - 29. ISSN: 1420-682X